Status:

TERMINATED

A Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Participants With Ichthyosis

Lead Sponsor:

Vanda Pharmaceuticals

Conditions:

Ichthyosis

Eligibility:

All Genders

12-75 years

Phase:

PHASE2

Brief Summary

Efficacy and Safety of imsidolimab in Participants with Ichthyosis

Detailed Description

This is a Phase 2, multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy, safety, and tolerability of imsidolimab compared with placebo in adolescent and adult parti...

Eligibility Criteria

Inclusion

  • Diagnosis of Ichthyosis
  • IASI total score ≥ 18, erythema score ≥ 2
  • Participant has been using emollient daily for at least 1 week prior to Day 1 and agrees to continue using that same emollient daily at the same frequency throughout the study

Exclusion

  • A participant with ichthyosis vulgaris, X-linked ichthyosis, or lamellar ichthyosis will be excluded.

Key Trial Info

Start Date :

January 25 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 19 2021

Estimated Enrollment :

5 Patients enrolled

Trial Details

Trial ID

NCT04697056

Start Date

January 25 2021

End Date

November 19 2021

Last Update

September 16 2025

Active Locations (7)

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Page 1 of 2 (7 locations)

1

Site 106

Palo Alto, California, United States, 94304

2

Site 104

New Haven, Connecticut, United States, 06519

3

Site 112

Miami, Florida, United States, 33125

4

Site 101

Chicago, Illinois, United States, 60611

A Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Participants With Ichthyosis | DecenTrialz