Status:
RECRUITING
Genetic Variants and Regulation of Specialized Pro-resolving Mediator
Lead Sponsor:
Queen Mary University of London
Conditions:
Healthy
Inflammatory Disease
Eligibility:
All Genders
18+ years
Brief Summary
Inflammation is the way that the body reacts against infection, injury or illness. An uncontrolled inflammatory response can lead to the development of inflammatory diseases, such as rheumatoid arthri...
Detailed Description
This study aims to identify polymorphisms in SPM-related genes in a South Asian population and assess whether these lead to alterations in the functions of enzymes and proteins encoded by these genes....
Eligibility Criteria
Inclusion
- Current volunteer of the Genes \& Health program with (test) or without (control) relevant genetic mutations. Genes \& Health is a huge long-term study of 100,000 people of Bangladeshi and Pakistani origin focuses to link genes with health records and to study disease and treatments. When a volunteer participates in this program, they agree to the possibility to be invited for further studies. Gene \& Health program invites volunteers to take part in two regions of the UK: East London and Bradford.
Exclusion
- Volunteer that has not had their genome sequenced after taking part in Stage 1 of Genes \& Health program.
- Volunteer with significant genetically inherited conditions.
- Any abnormality or pre-existing disease which, in the opinion of the investigator, might either expose the subject to risk, or influence the validity of the results.
- Volunteer that went under surgery and are recovering.
- Participation in a clinical study of a new chemical entity, biological product or a prescription medicine, or loss of more than 400 mL blood, within the previous 3 months.
- Presence or history of drug or alcohol abuse.
Key Trial Info
Start Date :
May 6 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 8 2025
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04698291
Start Date
May 6 2021
End Date
December 8 2025
Last Update
December 2 2024
Active Locations (1)
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1
Queen Mary University of London
London, United Kingdom, EC1M 6BQ