Status:
UNKNOWN
A Validation Study of Nitroglycerin Induced Acute Drop of Pd/Pa (NTG-Pd/Pa) in Clinical Practice
Lead Sponsor:
National Taiwan University Hospital Hsin-Chu Branch
Conditions:
Hypotension Symptomatic
Ischemic Heart Disease
Eligibility:
All Genders
21+ years
Brief Summary
Hyperemia with adenosine was an elemental process in FFR examination. Adenosine injection will induce some discomfort, and increase cost expenditure. Nitroglycerine will induce an acute drop of Pd/Pa,...
Detailed Description
Fractional flow reserve (FFR) is defined as the ratio of mean distal pressure (distal to the target lesion, Pd）to mean proximal pressure (aortic pressure, Pa) in the coronary artery(Pd/Pa) while the m...
Eligibility Criteria
Inclusion
- Eligible for FFR examination
Exclusion
- Hypersensitivity to adenosine or nitroglycerine
- Severe Valvular aortic stenosis
- Resting heart rate less than 50 beats per minutes
- Systolic blood pressure less than 100 mmHg or diastolic blood pressure less than 40 mmHg
- exposure to PDE-5 inhibitors within 48 hours.
- Recent intracranial hemorrhage or brain injury
Key Trial Info
Start Date :
January 2 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
February 29 2024
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04700397
Start Date
January 2 2021
End Date
February 29 2024
Last Update
January 7 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
National Taiwan University Hospital Hsin-Chu branch
Hsinchu, Taiwan, 300