Status:

UNKNOWN

Omega 3, Leucine, Probiotic Lactobacillus Paracasei PS23 on Muscle Mass in Sarcopenic Subjects

Lead Sponsor:

Azienda di Servizi alla Persona di Pavia

Collaborating Sponsors:

Abiogen Pharma

Conditions:

Sarcopenia

Elderly

Eligibility:

All Genders

55+ years

Phase:

NA

Brief Summary

The purpose of the study is to evaluate the effect of supplementation with a nutritional blend based on Omega 3 fatty acids, the probiotic leucine Lactobacillus paracasei PS23 (OLEP), on muscle mass r...

Eligibility Criteria

Inclusion

  • Sarcopenic patients (diagnosis made according to the criteria Revised European Consensus on Definition and Diagnosis)
  • Body Mass Index between 20 and 30 Kg/m2

Exclusion

  • severe renal failure (glomerular filtration rate \< 30 mL/min)
  • moderate to severe liver failure (Child-Pugh class B or C)
  • endocrine diseases associated with calcium metabolism disorders (except osteoporosis)
  • known psychiatric disorders
  • cancer (over the past 5 years)
  • hypersensitivity to any component of the investigational nutritional supplement and
  • taking to protein/amino acid supplements (up to 3 months before starting the study)
  • patients unable to take oral therapy
  • receiving or with indication for artificial nutrition
  • who had been included in another clinical nutrition trial

Key Trial Info

Start Date :

January 22 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2022

Estimated Enrollment :

54 Patients enrolled

Trial Details

Trial ID

NCT04702087

Start Date

January 22 2021

End Date

December 1 2022

Last Update

October 5 2021

Active Locations (1)

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Azienda di Servizi alla Persona

Pavia, Italy, 27100