Status:

COMPLETED

Identification of Pathophysiological Pathways and Therapeutic Targets in Primary Stomatodynia by Salivary Metabolomics

Lead Sponsor:

University Hospital, Tours

Conditions:

Primary Burning Mouth Syndrome

Eligibility:

FEMALE

18+ years

Brief Summary

Burning mouth syndrome (BMS) is defined by a chronic oral pain affecting especially postmenopausal women. Its physiopathology is still unknown and several hypotheses have been put forward to explain t...

Detailed Description

Burning mouth syndrome (BMS) is defined by a chronic oral pain affecting especially postmenopausal women. Its physiopathology is still unknown and several hypotheses have been put forward to explain t...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • For cases : primary Burning Mouth Syndrome, based on the IHS diagnosis criteria
  • For cases : being able to realise the salivary collection
  • For controls : no primary BMS
  • For controls : being able to realise the salivary collection
  • Exclusion Criteria for both groups:
  • Treatment by antibiotics in the previous month
  • New treatment in the previous two weeks
  • Active smoking
  • Active infectious or inflammatory oral disease
  • Systemic disease that could have an impact on the salivary metabolome or on the neurological system
  • Being under legal guardianship
  • Opposition to the processing of personal data

Exclusion

    Key Trial Info

    Start Date :

    March 10 2021

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    May 12 2021

    Estimated Enrollment :

    53 Patients enrolled

    Trial Details

    Trial ID

    NCT04704128

    Start Date

    March 10 2021

    End Date

    May 12 2021

    Last Update

    July 7 2021

    Active Locations (1)

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    Department of Dermatology, Hospital University of Tours

    Tours, France, 37044