Status:
ACTIVE_NOT_RECRUITING
Community Dynamics of Malaria Transmission in Humans and Mosquitoes in Fleh-la and Marshansue, Salala District, Bong County, Liberia
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Conditions:
Malaria
Eligibility:
All Genders
6+ years
Brief Summary
Background: Malaria is a disease that affects many people in Liberia. It is caused by germs (parasites) that are spread by mosquito bites. Researchers want to gather data that may help them understan...
Detailed Description
A vaccine that interrupts malaria transmission is critical to eradicate the disease, but improved assays are needed to measure the efficacy of vaccines. Transmission-blocking vaccines (TBVs) work by i...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Subject
- 6 months of age and above
- Known resident of Fleh-la and Marshansue or the surrounding villages and planning to remain for duration of study
- Willingness to allow stored laboratory specimens to be used for future research
- Acceptance and signature of the written informed consent and the assent for children aged 12-17 years who are not otherwise emancipated
- Household
- To be eligible for participation, households must meet the following criteria:
- Household with at least 3 residents eligible for participation.
- Household with at least one compound member who is below 18 years of age whose parents or caretakers are willing to provide informed consent for the child to participate.
- Household members willing to accommodate mosquito sampling in their compound, both indoors and outdoors.
Exclusion
- Subject
Key Trial Info
Start Date :
September 30 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 28 2026
Estimated Enrollment :
396 Patients enrolled
Trial Details
Trial ID
NCT04704674
Start Date
September 30 2021
End Date
February 28 2026
Last Update
January 9 2026
Active Locations (1)
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1
National Public Health Institute of Liberia (NPHIL)
Fleh-la, Liberia