Status:
COMPLETED
The Effects of Respiratory Training on Voice
Lead Sponsor:
Syracuse University
Conditions:
Muscle Tension Dysphonia
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Primary muscle tension dysphonia is a voice disorder that involves excessive and poorly coordinated muscle activity affecting multiple subsystems that are involved in speech production, in the absence...
Eligibility Criteria
Inclusion
- Ages 18 or older
- Self-report of general good health other than voice disorder
- Self-report of normal pulmonary function
- Non-smoker status for at least the last 5 years
- English as their primary language to avoid potential linguistically-based differences in acoustic measures of voice
- Adequate visual acuity (with or without corrective lenses) to read basic graphs and print, as determined with visual screening
- No evidence of current organic or neurologic laryngeal pathology, as assessed by nasolaryngoscopy examination and reviewed by a laryngologist
- No prior surgery to the vocal folds
- Do not report difficulty with swallowing
- Not currently receiving voice therapy or other voice treatment that cannot be discontinued
- Do not report a bilateral, severe to profound hearing loss
- Willingness to be recorded for data collection that is necessary for this study
- Have a confirming diagnosis of Muscle Tension Dysphonia from an otolaryngologist and speech-language pathologist
- Demonstrate quantified auditory-perceptual dysphonia and acoustic dysphonia (Cepstral/Spectral Index of Dysphonia) that exceed normative values for the participant's age and sex
- Based on the nasolaryngoscopy examination and assessment performed by the otolaryngologist, show one or more patterns of supraglottic activity that are consistent with adducted vocal fold hyperfunction
- Show no evidence of abnormal, incomplete vocal fold closure patterns as determined on the videostroboscopy assessment (patterns of posterior glottal gaps are normal and expected)
- Show no evidence of additional neurological voice disorders such as spasmodic dysphonia or vocal fold paralysis
- Show elevated hyolaryngeal position that exceeds normative expectations as determined through quantitative analysis of ultrasonographic laryngeal images measuring change from rest to phonation
- Demonstrate voice problems that have persisted for ≥2 months
- Demonstrate self-reported increase in speaking effort
- Show evidence of speech breathing abnormalities relative to accepted normative values
Exclusion
- Ages 17 or younger
- Self-report of major health problems
- Self-report of pulmonary disease such as asthma, chronic obstructive pulmonary disease, or emphysema
- Current smoker status or prior smoker status within the last 5 years
- English not the primary language
- Inadequate visual acuity (with corrective lenses if applicable) to read basic graphs and print as determined by failing a visual screening
- Evidence of current organic or neurologic laryngeal pathology, as assessed by nasolaryngoscopy examination and reviewed by a laryngologist
- Prior surgery to the vocal folds
- Currently receiving voice therapy or other voice treatment that cannot be discontinued
- Self-report of a bilateral, severe to profound hearing loss
- Not willing to be recorded for data collection that is necessary for this study
- No confirming diagnosis of Muscle Tension Dysphonia from an otolaryngologist and speech-language pathologist
- Do not demonstrate quantified auditory-perceptual dysphonia and acoustic dysphonia (Cepstral/Spectral Index of Dysphonia) that exceed normative values for the participant's age and sex
- Based on the nasolaryngoscopy examination and assessment performed by the otolaryngologist, do not show one or more patterns of supraglottic activity that are consistent with adducted vocal fold hyperfunction
- Show evidence of abnormal, incomplete vocal fold closure patterns as determined on the videostroboscopy assessment (patterns of posterior glottal gaps are normal and expected)
- Show evidence of additional neurological voice disorders such as spasmodic dysphonia or vocal fold paralysis
- Do not show elevated hyolaryngeal position that exceeds normative expectations as determined through quantitative analysis of ultrasonographic laryngeal images measuring change from rest to phonation
- Demonstrate voice problems that have persisted for less than 2 months
- Do not demonstrate self-reported increase in speaking effort
- Do not show evidence of speech breathing abnormalities relative to accepted normative values
Key Trial Info
Start Date :
May 12 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 23 2024
Estimated Enrollment :
27 Patients enrolled
Trial Details
Trial ID
NCT04710862
Start Date
May 12 2021
End Date
September 23 2024
Last Update
July 24 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Syracuse University
Syracuse, New York, United States, 13244