Status:
COMPLETED
Investigation of a New Human Model for Itch
Lead Sponsor:
Aalborg University
Conditions:
Itch
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
This third sub-project aims to evaluate the interaction between the TRPM8 receptor and pruritus by studying the anti-pruritic effect of TPRM8-agonist L-menthol on histaminergic and non-histaminergic i...
Eligibility Criteria
Inclusion
- Healthy men and women
- 18-60 years
- Speak and understand English
Exclusion
- Pregnancy or lactation
- Drug addiction defined as any use of cannabis, opioids or other addictive drugs
- Previous or current history of neurological, dermatological, immunological musculoskeletal, cardiac disorder or mental illnesses that may affect the results (e.g. neuropathy, muscular pain in the upper extremities, etc.).
- Lack of ability to cooperate
- Current use of medications that may affect the trial such as antihistamines, antipsychotics and pain killers, as well as systemic or topical steroids.
- Skin diseases
- Moles, scars or tattoos in the area to be treated or tested.
- Hypersensitivity to papaya and mango fruit, cashew nuts, rubber latex
- Consumption of alcohol or painkillers 24 hours before the study days and between these
- Acute or chronic pain
- Participation in other trials within 1 week of study entry (4 weeks in the case of pharmaceutical trials)
Key Trial Info
Start Date :
February 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 5 2021
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT04711044
Start Date
February 1 2021
End Date
July 5 2021
Last Update
July 9 2021
Active Locations (1)
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1
Aalborg University
Aalborg, North Denmark, Denmark, 9229