Status:

WITHDRAWN

Efficacy of Envarsus XR and Digital Health Technology in Reducing Tacrolimus Fluctuation and Frequency of Dose Changes

Lead Sponsor:

Beth Israel Deaconess Medical Center

Collaborating Sponsors:

Veloxis Pharmaceuticals

Conditions:

Medication Adherence

Renal Transplant

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Tacrolimus is an immunosuppressive agent prescribed to prevent organ rejection in post transplant patients, in combination with other immunosuppressants. In post-kidney transplant patients, tacrolimus...

Detailed Description

Tacrolimus is a calcineurin-inhibitor immunosuppressant indicated for the prophylaxis of organ rejection in patients receiving allogeneic liver, kidney or heart transplants, in combination with other ...

Eligibility Criteria

Inclusion

  • BIDMC adult kidney transplant recipient more than 2 years post transplant
  • On tacrolimus IR regimen
  • Estimated glomerular filtration rate (eGFR) \>45
  • Tacrolimus dose adjustments 2 or more times in past 12 months
  • Own and able to use a smart phone.
  • Able to consent

Exclusion

  • Prisoners
  • Patients with primary language other than English, Spanish, Haitian/Creole, Mandarin
  • Patients who can't swallow whole tablets or capsules.

Key Trial Info

Start Date :

June 1 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2023

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT04711291

Start Date

June 1 2017

End Date

July 1 2023

Last Update

August 9 2024

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Efficacy of Envarsus XR and Digital Health Technology in Reducing Tacrolimus Fluctuation and Frequency of Dose Changes | DecenTrialz