Status:

UNKNOWN

Comprehensive Study on Dry Eye and Ocular Surface Disease Prior and After Cataract Surgery

Lead Sponsor:

Fundación Oftalmológica Los Andes

Collaborating Sponsors:

Alcon Research

Conditions:

Dry Eye Disease

Dry Eye Syndrome

Eligibility:

All Genders

18-99 years

Phase:

PHASE3

Brief Summary

Ocular surface disease (OSD), particularly dry eye, is one of the most common conditions seen by ophthalmologists. Dry eye (DE) is a multifactorial disease of the tears and ocular surface that results...

Detailed Description

A prospective randomized study has been designed to assess and characterize OSD/DE in consecutive patients presenting for cataract surgery evaluation and to identify eventual changes on biomarkers of ...

Eligibility Criteria

Inclusion

  • 18 years or older
  • Indication of phacoemulsification for refractive purposes or for the presence of visually significant cataract.
  • Absence of intraoperative or postoperative complications of phacoemulsification
  • Willing to participate in the study (signed informed consent)

Exclusion

  • Ocular surgeries within the previous 6 months.
  • Contact lenses user.
  • Severe blepharitis.
  • Palpebral malposition and secondary dry eye
  • History of filamentary keratitis, corneal neovascularization, or herpetic keratitis within previous 3 months.
  • Hypersensitivity to investigated substances or diagnostic stains used.
  • Antiglaucomatous topical medication
  • Artificial tears with instillation frequency greater than 3 times a day in the last week

Key Trial Info

Start Date :

January 15 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 15 2023

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04711642

Start Date

January 15 2021

End Date

July 15 2023

Last Update

January 15 2021

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