Status:
UNKNOWN
Bloodflow Restricted Exercise in Healthy Ageing
Lead Sponsor:
University of Aarhus
Conditions:
Aging
Eligibility:
All Genders
45-80 years
Phase:
NA
Brief Summary
The overall objective of this study is to investigate the efficacy of low-intensity blood flow restricted resistance exercise (BFRRE) to promote health beneficial skeletal muscle adaptations and augme...
Eligibility Criteria
Inclusion
- Able to understand the written and spoken information and to give informed consent for inclusion.
- Age between 45 and 80 years
- Able to sit in a knee extension machine
- Able to deliver muscle biopsies
- Able to train 3 times per week during a 6-week period
Exclusion
- Known history of cardiac disease
- Habitual exercise with high intensity \> 2 times pr. week within the past 6 months
- Pregnancy
- Diabetes mellitus
- Peripheral neuropathy
- Dialysis treatment
- Severe peripheral arterial disease
- Concomitant acute life threatening medical condition
- Intracranial aneurisms, arteriovenous malformation, cerebral neoplasm or abscess
- Severe arterial hypertension (≥ 180/≥ 110 mmHg) or moderate arterial hypertension (160-179/100-109) despite medical treatment
- Moderate or severe chronic obstructive pulmonary disease
- Decreased kidney function - eGFR \< 60 ml/min
Key Trial Info
Start Date :
January 19 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2025
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT04712955
Start Date
January 19 2021
End Date
July 1 2025
Last Update
January 19 2021
Active Locations (1)
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1
University of Aarhus
Aarhus, Denmark, 8000