Status:
UNKNOWN
Supplementation of Brown Seaweed on Insulin Resistance of NAFLD Patients With Pre- or Type 2-Diabetes
Lead Sponsor:
Taipei Medical University WanFang Hospital
Collaborating Sponsors:
Hi-Q Marine Biotech International, Ltd.
Conditions:
Type II Diabetes
Eligibility:
All Genders
20-75 years
Phase:
NA
Brief Summary
Investigators research team conducted a previous human clinical trial of brown algae and conducted liver and metabolic indicators of brown algae to improve nonalcoholic fatty liver disease, and found ...
Detailed Description
Brown seaweeds rich in flavonoids and bioactive polysaccharides have been shown the potential effects on suppressing fat accumulation, oxidative stress and inflammation in liver. The refined seaweed c...
Eligibility Criteria
Inclusion
- Between the ages of 20 and 75 years old, biochemical test data and abdominal ultrasound screening were selected according to the following conditions.
- Prediabetes: AC at 101 to 125 and HbA1c at 5.8 to 6.4 and abdominal ultrasound confirmed fatty liver.
- Type 2 Diabetes: Abdominal ultrasound confirms the presence of fatty liver; Hypoglycemic agent HbA1c controls 8% (but does not contain Pioglitazone or injection of Liraglutide), or patient HbA1c is controlled below 9% but does not want to increase drug Dosage or add other hypoglycemic agents.
Exclusion
- Severe renal insufficiency (diabetic or eGFR less than 30 mL/min/1.73 m2), severe heart failure (NYHA function classification III or IV), etc.
- Allergies to seafood and seaweed ingredients.
- Cannot or refuse to sign test consent.
- Inject insulin or Liraglutide or take Pioglitazone.
- Type 1 diabetes patients.
- People who drink alcohol and take weight-related drugs and health products.
- There are blood transfusion recipients within three months.
Key Trial Info
Start Date :
December 10 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 28 2021
Estimated Enrollment :
106 Patients enrolled
Trial Details
Trial ID
NCT04715776
Start Date
December 10 2018
End Date
February 28 2021
Last Update
January 20 2021
Active Locations (1)
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1
Wanfang Hospital
Taipei, Wenshan District, Taiwan, 116