Status:
UNKNOWN
Impact of Ionizing Treatment on the Nuclear Structure of Human Spermatozoa.
Lead Sponsor:
University Hospital, Clermont-Ferrand
Collaborating Sponsors:
Agence de La Biomédecine
Conditions:
Sperm Preservation
Irradiated Semen
Eligibility:
MALE
18-45 years
Brief Summary
Differentiated thyroid cancer is the third cause of cancer in young men of childbearing age. Its treatment by irradiation with Radioactive Iodine 131 therapy (RAT) could alter spermatogenesis and resu...
Detailed Description
Our main objective is to measure the in vitro impact of irradiation treatment on sperm nuclear quality such as DNA fragmentation and oxidation, chromatin condensation and organisation, nucleus morphol...
Eligibility Criteria
Inclusion
- Man less than 45 years
- Man undergoing routine semen analysis at the Center for Reproductive Medicine, accepting the research protocol and signing the associated consent will be included in the protocol without distinction of physical criteria.
Exclusion
- \-
Key Trial Info
Start Date :
January 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2022
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04715828
Start Date
January 1 2018
End Date
January 1 2022
Last Update
January 20 2021
Active Locations (1)
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1
CHU de Clermont-Ferrand
Clermont-Ferrand, France, 63000