Status:

COMPLETED

Biomechanical and Neurophysiological Evaluation of the Effect of a Motor Block and an Injection of Botulinum Toxin on the Stiffness of the Paretic Sural Triceps Muscle

Lead Sponsor:

Nantes University Hospital

Conditions:

Cerebrovascular Accident

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

The research "Biomechanical and neurophysiological evaluation of the effects of a motor block and an injection of botulinum toxin on the stiffness of the paretic sural triceps muscle" will study the r...

Detailed Description

Following a stroke, patients see their motor function impaired, in particular by the establishment of muscular retractions. These affect motor performance of the patients, as for example by impairing ...

Eligibility Criteria

Inclusion

  • Inclusion Criteria :
  • Patient with signed consent,
  • Be over 18 and under 80 years of age,
  • Have suffered a stroke (medical diagnosis),
  • Spasticity of the triceps surae with a modified Ashworth score of the triceps sural of at least 1,
  • Medical indication to perform a treatment of spasticity of the sural triceps by ITB, requiring a prior selective nerve block to qualify or disqualify this procedure (depending on the effectiveness, reaction / sensations / perceptions of the patient),
  • Cognitive abilities compatible with experimentation: absence of language or judgment impairments that prevent the understanding of the research or the expression of agreement. An aphasia severity score \> or equal to 3 will be required for inclusion,
  • Be eligible for social security.
  • Exclusion Criteria:
  • Person in an emergency situation, deprived of liberty, or not benefiting from the social protection system,
  • Person under 18 years of age or under any legal protection measure whatsoever,
  • Unbalanced epileptic disorder; tension variability,
  • History of calf surgery (scarring areas that disrupt ultrasound elastography exploration),
  • Disorders related to bed rest: thromboembolic disorders, bedsores, respiratory or digestive disorders,
  • Previous botulinum toxin injection injection less than 3 months ago (contraindication to a new botulinum toxin injection),
  • Contraindication to an injection of botulinum toxin abobotulinum toxin A (Dysport®),
  • Patient under anti-coagulant,
  • Aphasia or cognitive impairment interfering with task comprehension,
  • Contraindication to ankle manipulation: fracture, phlebitis, pressure sore in the areas of support of the orthosis,
  • Pregnant or breastfeeding women.
  • Translated with www.DeepL.com/Translator (free version)

Exclusion

    Key Trial Info

    Start Date :

    February 3 2021

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    July 10 2023

    Estimated Enrollment :

    27 Patients enrolled

    Trial Details

    Trial ID

    NCT04717141

    Start Date

    February 3 2021

    End Date

    July 10 2023

    Last Update

    July 24 2023

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    CHU de Nantes

    Nantes, France

    Biomechanical and Neurophysiological Evaluation of the Effect of a Motor Block and an Injection of Botulinum Toxin on the Stiffness of the Paretic Sural Triceps Muscle | DecenTrialz