Status:
COMPLETED
Comparative Study: Vaginal Promestriene Use, Fractional CO2 LASER and Radiofrequency in the Vaginal Atrophy Treatment
Lead Sponsor:
University of Sao Paulo General Hospital
Conditions:
Vaginal Atrophy
Eligibility:
FEMALE
40-65 years
Phase:
NA
Brief Summary
Postmenopausal hypoestrogenism may determine genital atrophy, which may be accompanied by a non-specific inflammatory process and may hinder or even prevent sexual intercourse. In more severe cases, t...
Detailed Description
After completing the eligibility criteria, patients signed the consent inform. Division of groups: Were included in the study 75 patients, divided into three groups: Group 1 - Treatment with topica...
Eligibility Criteria
Inclusion
- Age equal or superior to 40 years and under 65 years
- Clinical menopause - last menstrual period from 1 to 5 years from the date of recruitment
- FSH measurement\> 25 IU / ml, estrogen \<20 æg / ml
- Patients with vaginal atrophy and clinical and / or sexual symptoms
- Patients without hormonal treatment for at least five years
Exclusion
- Whole Hymen
- Altered oncology cytology of the cervix and / or vagina
- Vaginal infections
- Connective tissue diseases
- Immunosuppression
- Coagulation change
- Diabetes Mellitus
- Thyroid diseases
- Use of systemic or local feminine hormones
- Use of other substances with estrogenic properties
Key Trial Info
Start Date :
October 25 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 18 2020
Estimated Enrollment :
75 Patients enrolled
Trial Details
Trial ID
NCT04717245
Start Date
October 25 2018
End Date
February 18 2020
Last Update
January 25 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Disciplina de ginecologia - departamento de ginecologia e obstetrícia - faculdade de medicina da USP
São Paulo, Brazil, 01246-100