Status:
UNKNOWN
Revascularization Pretreated With Fingolimod in Acute Stroke
Lead Sponsor:
The Affiliated Hospital of Xuzhou Medical University
Conditions:
Stroke
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Acute ischemic stroke (AIS) is a common type of stroke in the elderly. Timely blood flow recovery can effectively improve the long-term prognosis of patients. According to five large-scale multicenter...
Eligibility Criteria
Inclusion
- The patient was over 18 years old;
- The NIHSS score was \< 30 and NIHSS \> 5;
- CTA / MRA / DSA confirmed occlusion of M1 segment of internal carotid artery or middle cerebral artery, and aspect score ≥ 6;
- CTP or MRI showed mismatch (ischemic core volume \< 70ml, CTP mismatch \> 1.2
- Normal to random time within 24 hours
- Written informed consent signed by patients or their families
Exclusion
- Standard contraindications to alteplase or mechanical thrombectomy
- Cerebral hemorrhage confirmed by imaging
- Cardiovascular diseases (such as bradycardia, etc.)
- Systolic blood pressure \> 185mmhg or diastolic blood pressure \> 110mmhg, and oral antihypertensive drugs can not be controlled
- Pregnant or lactating women
Key Trial Info
Start Date :
February 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 31 2022
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT04718064
Start Date
February 1 2021
End Date
January 31 2022
Last Update
January 22 2021
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