Status:

UNKNOWN

PERIODONTAL HEALTH IN PATIENTS ACUTELY ADMITTED FOR MYOCARDIAL INFARCTION: A CASE CONTROL STUDY

Lead Sponsor:

University of Aberdeen

Conditions:

Myocardial Infarction, Acute

Periodontitis

Eligibility:

All Genders

20-90 years

Brief Summary

Heart attack remains a major cause of death in adult population worldwide and especially within Scotland. A large portion of the general population has an increased risk of suffering from a heart atta...

Detailed Description

Coronary artery disease (CAD) is a multifactorial condition leading to most cases of myocardial infarction and results from interaction of genetic, lifestyle and environmental factors. However, as man...

Eligibility Criteria

Inclusion

  • cases: Patients aged 20-90 admitted with acute myocardial infarction
  • controls: Dental patients, aged 20-90, matched to patients in the case study group for age, gender (±7) and risk factors for coronary artery disease (hypertension, obesity, diabetes, smoking, hypercholesterolaemia) but with no history of myocardial infarction)

Exclusion

  • Severe co-morbidities, Inability to consent, pregnant participants will be excluded, participants with other systemic inflammatory diseases, patients taking antimicrobials or antibiotics in last three years, patients taking medications, such as cyclosporine, calcium channel blockers, phenytoin, immunocompromised patients, patients with malignancies, patinets with type-2 or type-3 hypersensitivities

Key Trial Info

Start Date :

February 16 2018

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2022

Estimated Enrollment :

320 Patients enrolled

Trial Details

Trial ID

NCT04719026

Start Date

February 16 2018

End Date

December 31 2022

Last Update

January 22 2021

Active Locations (1)

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1

Dr Karolin Hijazi

Aberdeen, United Kingdom, AB25 2ZR