Status:
COMPLETED
Reversal of Neuromuscular Blockade and Perioperative Arrhythmias
Lead Sponsor:
Başakşehir Çam & Sakura City Hospital
Collaborating Sponsors:
Medipol University
Conditions:
Neuromuscular Blockade
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
Patients scheduled for elective abdominopelvic laparoscopic surgery under general anesthesia were included. Rocuronium was used for the neuromuscular blockade (NMB) and the level of NMB was monitored ...
Detailed Description
Eighty consecutive patients, to whom an elective abdominopelvic surgery under general anesthesia was planned, were included in the study. Participants were allocated to two groups considering the agen...
Eligibility Criteria
Inclusion
- Planned abdominopelvic surgery under general anesthesia
- ASA II-IV
- Willing to give consent
Exclusion
- Significantly impaired left ventricular systolic function (ejection fraction \< 40%)
- Significant ongoing arrhythmia (sinus bradycardia with a heart rate below 40 beats/min, Mobitz Type II or 3rd-grade atrioventricular block, persistent or permanent atrial flutter or fibrillation, bigeminal or trigeminal ventricular premature beats, documented ventricular tachycardia)
- Severely reduced renal function (glomerular filtration rate \< 30 ml/min/1.73 m2)
- Severe respiratory diseases, neuromuscular disorders, and known allergy to anesthetic agents or adjuvants
- Pregnancy and breastfeeding
- Observing the typical signs of a channelopathy (short QT syndrome, long QT syndrome, Brugada syndrome, etc.) and history of recent medical therapy with agents exhibiting a high probability of QT prolongation
Key Trial Info
Start Date :
June 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2019
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT04720573
Start Date
June 1 2019
End Date
November 1 2019
Last Update
January 22 2021
Active Locations (1)
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1
Istanbul Medipol University
Istanbul, Turkey (Türkiye), 34214