Status:

COMPLETED

A Study of Velaglucerase Alfa (VPRIV) Given as Standard Patient Care in Young Children With Gaucher Disease

Lead Sponsor:

Takeda

Conditions:

Gaucher Disease

Eligibility:

All Genders

Up to 5 years

Brief Summary

The main aim of this study is to learn if velaglucerase alfa (VPRIV) improves growth and symptoms in participants up to 5 years of age with Gaucher disease. Symptoms will be checked with blood tests. ...

Eligibility Criteria

Inclusion

  • The participant's caregiver is able and willing to provide informed consent.
  • The participant is male or female younger than or equal to 4 years of age at treatment initiation.
  • The participant has received and confirmed a current diagnosis of GD type 1 or type 3 (biochemically and/or genetically).
  • The participant has been receiving intravenous (IV) Velaglucerase alfa treatment for GD.
  • In the opinion of the investigator, the participant's caregiver is capable of understanding and complying with protocol requirements.
  • The participant's legally acceptable representative signs and dates a written, informed consent form and any required privacy authorization prior to the initiation of any study procedures.

Exclusion

  • The participant is an immediate family member, study site employee, or is in a dependent relationship with a study site employee who is involved in conduct of this study (e.g., child, sibling) or may consent under duress.
  • The participant is judged by the investigator as being ineligible for any other reason.

Key Trial Info

Start Date :

January 8 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 17 2023

Estimated Enrollment :

11 Patients enrolled

Trial Details

Trial ID

NCT04721366

Start Date

January 8 2021

End Date

April 17 2023

Last Update

March 29 2024

Active Locations (1)

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Lysosomal & Rare Disorders Research & Treatment Center

Fairfax, Virginia, United States, 22030