Status:

RECRUITING

The HPV 9-10 Trial: Early Initiation of HPV Vaccination

Lead Sponsor:

University of Colorado, Denver

Collaborating Sponsors:

National Institutes of Health (NIH)

National Cancer Institute (NCI)

Conditions:

HPV

Eligibility:

All Genders

9-13 years

Phase:

NA

Brief Summary

Every year, thousands of Americans die from cancers related to human papillomavirus (HPV). The vast majority of those deaths could be prevented with a safe and effective vaccine, yet many parents choo...

Detailed Description

The burden of Human Papillomavirus (HPV)-related disease in the US is substantial. A safe and effective vaccine has been available for \>10 years, yet the current rate of completion for the HPV series...

Eligibility Criteria

Inclusion

  • Practices:
  • Practices in Metro Denver, Colorado and Metro Los Angeles, California (specifically UCLA medical clinics and clinics affiliated with Children's Hospital of Orange County)
  • Practices that have at least 60% of providers agree to participate
  • Practices do not currently recommend HPV at 9-10 years.
  • Practice must have at least 100 eligible patients age 9-13 years

Exclusion

  • Practices with less than 100 eligible patients age 9-13 years
  • Practices currently routinely recommend HPV vaccine at 9-10 years.
  • Practices where less than 60% of providers agree to participate in the study.
  • Patient Eligibility Criteria
  • Patient age 9-13 years
  • Seen at a participating practice in the last 3 years
  • Due for at least 1 dose of HPV vaccine

Key Trial Info

Start Date :

December 23 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 1 2027

Estimated Enrollment :

3100 Patients enrolled

Trial Details

Trial ID

NCT04722822

Start Date

December 23 2019

End Date

April 1 2027

Last Update

October 21 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

University of California at Los Angeles

Los Angeles, California, United States, 90095

2

University of Colorado

Aurora, Colorado, United States, 80045