Status:

COMPLETED

Pragmatic Randomized Clinical Trial to Limit Weight Gain in Pregnancy and Prevent Obesity

Lead Sponsor:

Johns Hopkins University

Collaborating Sponsors:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Conditions:

Pregnancy Weight Gain

Postpartum Weight Retention

Eligibility:

FEMALE

18+ years

Phase:

NA

Brief Summary

Healthy for Two, Healthy for You (H42/H4U) is an innovative evidence-based pregnancy/postpartum health coach intervention that is remotely-delivered (phone coaching using motivational interviewing, we...

Detailed Description

Despite two decades of public health efforts to combat obesity, rates continue to rise and racial disparities persist. There is an urgent need to re-focus obesity prevention efforts onto young adults,...

Eligibility Criteria

Inclusion

  • Age≥18
  • Singleton pregnancy
  • ≤15 weeks gestation with documented prenatal weight and height in electronic health record
  • Body mass index ≥ 25.0 kg/m2
  • English-speaking
  • Has smartphone, laptop or tablet and willing to use it for this study
  • Has email address and willing to use for this study

Exclusion

  • BMI \<25 kg/m2
  • Multiple fetuses
  • History of pre-gestational Type 1 or Type 2 diabetes or taking diabetes medication for treatment of diabetes prior to first prenatal visit
  • Prior history of severe preeclampsia, pre-term birth (\< 32 weeks gestation)
  • Poorly controlled blood pressure (\> 160/100 mmHg)
  • Substance use disorder or positive urine toxicology (except for THC) for illicit substances (screening done as part of routine care)
  • Psychiatric hospitalization in last 12 months or diagnosis of severe mental illness that is not well controlled
  • Active diagnosis of an eating disorder
  • Unable to walk 1 block without pain or shortness of breath
  • No email address
  • Unable to speak or read in English
  • Planning to move in next 12 months

Key Trial Info

Start Date :

March 15 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 25 2025

Estimated Enrollment :

534 Patients enrolled

Trial Details

Trial ID

NCT04724330

Start Date

March 15 2021

End Date

June 25 2025

Last Update

September 10 2025

Active Locations (1)

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Johns Hopkins Health System and University

Baltimore, Maryland, United States, 21205