Status:
COMPLETED
Effect of GnRH Agonist vs GnRH Antagonist on Oocyte Morphology During IVF/ICSI
Lead Sponsor:
Damascus University
Conditions:
In Vitro Fertilization
Intracytoplasmic Sperm Injection
Eligibility:
FEMALE
18-39 years
Phase:
PHASE4
Brief Summary
Selection of developmentally competent oocytes enhances IVF efficiency. Usually, oocyte quality is determined based on its nuclear maturation and the presence of specific cytoplasmic and extracytoplas...
Eligibility Criteria
Inclusion
- Women undergoing IVF/ICSI.
- Age: 18-39 years.
- Both ovaries present.
Exclusion
- Age ≥ 40 years
- History of three or more previous IVF failures.
- Patients with hormonal disorders like hyperprolactinemia, thyroid disorders.
- Patients with Polycystic Ovarian Syndrome.
- Patients who previously undergo Unilateral Oophorectomy.
- Patients with chronic diseases: diabetes mellitus, cardiovascular diseases, liver diseases, kidney diseases.
- Patients with diseases may affect IVF outcomes: Endometriosis, uterine fibroids, Hydrosalpinx, Adenomyosis, autoimmune diseases,
- Cancer.
Key Trial Info
Start Date :
August 22 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 15 2022
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT04724486
Start Date
August 22 2020
End Date
July 15 2022
Last Update
October 24 2023
Active Locations (1)
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1
Orient Hospital
Damascus, Syria