Status:

COMPLETED

Clinical Evaluation of Florbetapir in Primary Progressive Aphasia

Lead Sponsor:

University of Chicago

Conditions:

Primary Progressive Aphasia

Alzheimer Disease

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this research is to better understand how dementia affects activity in different parts of the brain.

Detailed Description

This study is being done to examine the usefulness of Positron Emission Tomography (PET) imaging with florbetapir F 18 as a biomarker in the identification of amyloid-ß peptide (Aß) in the brain. Amyl...

Eligibility Criteria

Inclusion

  • Subjects who, in the opinion of the investigator, can tolerate the PET scan procedures

Exclusion

  • Clinically significant cardiovascular disease
  • clinically significant hepatic, renal, pulmonary, metabolic, or endocrine disturbances
  • Pregnant
  • Breastfeeding
  • Women of childbearing potential who are not surgically sterile, not refraining from sexual activity or not using reliable methods of contraception.
  • History of relevant severe drug allergy or hypersensitivity
  • Patients who have received an investigational medication under an FDA Investigational New Drug (IND) protocol within the last 30 days.

Key Trial Info

Start Date :

March 15 2012

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

February 28 2017

Estimated Enrollment :

48 Patients enrolled

Trial Details

Trial ID

NCT04726527

Start Date

March 15 2012

End Date

February 28 2017

Last Update

October 16 2024

Active Locations (1)

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The Healthy Aging & Alzheimer's Research Care Center - University of Chicago

Chicago, Illinois, United States, 60637