Status:

UNKNOWN

The Modulatory Role of Internet MBCT on Extracellular Vesicles and Distress in Cancer Patients - Study Protocol

Lead Sponsor:

Instituto Portugues de Oncologia, Francisco Gentil, Porto

Collaborating Sponsors:

European Commission

University of Coimbra

Conditions:

Cancer

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

Mindfulness-based interventions (MBIs), such as mindfulness-based stress reduction (MBSR), mindfulness-based cognitive therapy (MBCT), mindfulness-based cancer recovery (MBCR), have been showing promi...

Eligibility Criteria

Inclusion

  • Diagnosis of breast, prostate, or colorectal cancer;
  • Cancer stage I - III;
  • Primary cancer treatments completed between 3 months and 5 years (participants with ongoing adjuvant hormonal therapies will be included);
  • Age between 18 and 65 years;
  • Experiencing significant distress on the Distress Thermometer (DT ≥ 4)
  • Willingness to accept randomization to one of the two study conditions and to attend the study for its duration;
  • Ability to speak, read, and write in Portuguese and literacy to complete autonomously the self-report measures;
  • Sufficient digital literacy with access to a device (e.g., smartphone; tablet; computer) with camera, microphone, and internet.

Exclusion

  • Concurrent diagnosis of severe psychiatric condition(s) (e.g., psychosis; substance abuse; bipolar disorder; suicidal ideation);
  • Concurrent diagnosis of autoimmune disorder;
  • Current use of antipsychotics;
  • Current use of anti-inflammatory medication (corticotherapy);
  • Undergoing trastuzumab therapy;
  • Participation in a structured mindfulness program (e.g., MBCT; MBSR; Mindfulness-Based Cancer Recovery - MBCR) program in the past five years;
  • Currently attending psychological consultation;
  • Being pregnant or breastfeeding.

Key Trial Info

Start Date :

September 3 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 31 2024

Estimated Enrollment :

111 Patients enrolled

Trial Details

Trial ID

NCT04727593

Start Date

September 3 2021

End Date

March 31 2024

Last Update

September 5 2023

Active Locations (1)

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Instituto Português de Oncologia do Porto Francisco Gentil, EPE

Porto, Portugal, 4200-072