Status:

COMPLETED

Pharmacogenomic-Guided Supportive Care in Hematopoietic Cell Transplantation

Lead Sponsor:

Wake Forest University Health Sciences

Conditions:

Hematopoietic Cell Transplantation

Oncology

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Hematopoietic cell transplantation (HCT) is the only curative treatment modality for many hematologic malignancies. Morbidity and mortality rates have declined drastically over the years, secondary to...

Detailed Description

The investigators hypothesize that the implementation of a pharmacist-driven precision medicine service guided by HCT clinical pharmacists and Specialty Pharmacy pharmacists using preemptive pharmacog...

Eligibility Criteria

Inclusion

  • Written informed consent and HIPAA authorization for release of personal health information
  • Age ≥ 18 years at the time of consent
  • Scheduled HCT (allogeneic and autologous, any conditioning regimen) treatment for any malignant or non-malignant indications (i.e. aplastic anemia)
  • Ability to read and understand English or Spanish
  • Able to provide a buccal sample for DNA extraction and genotyping

Exclusion

  • Psychiatric illness/social situations, or active/recent (within 30 days) history of elicit substance abuse that would limit compliance with study requirements as determined by the investigator

Key Trial Info

Start Date :

February 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 9 2023

Estimated Enrollment :

110 Patients enrolled

Trial Details

Trial ID

NCT04727827

Start Date

February 1 2021

End Date

June 9 2023

Last Update

August 3 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Levine Cancer Institute

Charlotte, North Carolina, United States, 28204