Status:
COMPLETED
Associations Between COVID-19 ARDS Treatment, Clinical Trajectories and Liberation From Mechanical Ventilator - an Analysis of the NorthCARDS Dataset
Lead Sponsor:
Northwell Health
Collaborating Sponsors:
BioSymetrics
Feinstein Institute for Medical Research
Conditions:
ARDS, Human
Covid19
Eligibility:
All Genders
Brief Summary
The mortality rates associated with COVID-19 related ARDS (COVIDARDS) have varied from observational reports from around the world. This has ranged from 44% (28 day mortality) in the UK to 36% (28 day...
Detailed Description
The investigators will leverage the NorthCARDS dataset for this analysis. This dataset includes over 1500 persons admitted to the Northwell Health System who had PCR positive COVID19 testing and were ...
Eligibility Criteria
Inclusion
- Inpatients at any of the hospitals within the Northwell Health system
- COVID19 PCR positive
- meeting ARDS criteria (defined as)
- PaO2:FiO2 \<300 for at least 2 consecutive values (including 2 S/F values)
- bilateral infiltrates
- mechanical ventilation (NIMV or IMV with PEEP 5)
- Timeframe March 1, 2020 until December 30, 2020
Exclusion
- Patients admitted for surgical procedures
- infiltrates described as being due to cardiogenic pulmonary edema without COVID-19 pneumonia
- improvement of paO2:FiO2 to \> 300 within 48 hours
Key Trial Info
Start Date :
January 19 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 19 2021
Estimated Enrollment :
1800 Patients enrolled
Trial Details
Trial ID
NCT04729075
Start Date
January 19 2021
End Date
January 19 2021
Last Update
April 4 2023
Active Locations (1)
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1
Feinstein Institutes for Medical Research
Manhasset, New York, United States, 11030