Status:
NOT_YET_RECRUITING
Comparison of Targeting Methods for Transcranial Magnetic Stimulation Treatment of Depression
Lead Sponsor:
Stanford University
Conditions:
Depression
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
We aim to learn whether use of a mixed reality device for transcranial magnetic stimulation (TMS) targeting can improve treatment outcomes compared to targeting through scalp measurements or a commerc...
Detailed Description
Prior studies suggest that treatment efficacy for TMS treatment of depression is affected by the targeting method used to guide TMS coil placement. We will compare the treatment outcome for three pati...
Eligibility Criteria
Inclusion
- Male or female subjects ages 18-75.
- MRI scanning eligibility, including no evidence of any form of metal embedded in the body (e.g., metal wires, nuts, bolts, screws, plates, sutures), as these produce artifacts when brain imaging. All potential subjects for the MRI component will need to successfully complete the screening forms at the Stanford Center for Cognitive and Neurobiological Imaging (CNI) or the Lucas Center. Those subjects who present no contraindications to being scanned will be allowed to participate.
- Healthy subjects with no history of any Axis I psychiatric disorder, are taking psychotropic medication, or use illicit drugs.
- Clinical subjects with a diagnosis of treatment resistant depression and prescribed a clinical course of treatment with rTMS.
Exclusion
- Any contraindication to being scanned in the 3.0T scanner at the Lucas Center or CNI such as having a pacemaker or implanted device that has not been cleared for scanning at 3.0 Tesla.
- History of neurological disorders including but not limited to brain surgery, deep brain stimulation, radiation treatment, brain hemorrhage or tumor, stroke, seizures or epilepsy, head trauma.
Key Trial Info
Start Date :
January 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT04730180
Start Date
January 1 2024
End Date
December 31 2026
Last Update
May 7 2021
Active Locations (1)
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1
Stanford University
Stanford, California, United States, 94305