Status:
UNKNOWN
Evaluation of a Synbiotic Formula in Patient With COVID-19
Lead Sponsor:
Chinese University of Hong Kong
Conditions:
Coronavirus
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
A series of microbiota were correlated inversely with the disease severity and virus load. Gut microbiota could play a role in modulating host immune response and potentially influence disease severit...
Detailed Description
Coronavirus can target multiple organs due to the hyperactive immune response with cytokine storms. Several studies have detected SARS-CoV-2 in stool samples and indicated that the virus could spread ...
Eligibility Criteria
Inclusion
- Aged 18 or above; and
- A confirmed diagnosis of SARS-Cov.2 infection using the PCR according to the standard of according to Centre for Health Protection, Department of Health, HK and released from isolation at recruitment.
- Written informed consent obtained
Exclusion
- Known allergy or intolerance to the intervention product or its components
- Any known medical condition that would prevent taking oral probiotics or increase risks associated with probiotics including but not limited to inability to swallow/aspiration risk and no other methods of delivery (e.g., no G/J tube)
- Known increased infection risk due to immunosuppression such as:
- Prior organ or hematopoietic stem cell transplant
- Neutropenia (ANC \<500 cells/ul)
- HIV and CD4 \<200 cells/ul
- Known increased infection risk due to endovascular due to:
- Rheumatic heart disease
- Congenital heart defect,
- Mechanical heart valves
- Endocarditis
- Endovascular grafts
- Permanent endovascular devices such as permanent (not short-term) hemodialysis catheters, pacemakers, or defibrillators
- Documented pregnancy
Key Trial Info
Start Date :
August 25 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 31 2022
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT04730284
Start Date
August 25 2020
End Date
March 31 2022
Last Update
January 29 2021
Active Locations (1)
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1
Chinese University of Hong Kong
Hong Kong, Hong Kong