Status:
RECRUITING
Pre- Vs Postoperative Thromboprophylaxis for Liver Resection
Lead Sponsor:
Helsinki University Central Hospital
Collaborating Sponsors:
Academy of Finland
The Finnish Medical Association
Conditions:
Liver Cancer
Surgery
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
Thromboprophylaxis for liver surgery can be commenced either preoperatively or postoperatively. Despite a clear trade-off between thrombosis and bleeding in liver surgery patients, there is no interna...
Eligibility Criteria
Inclusion
- All patients undergoing liver resection
Exclusion
- Patient on anticoagulative medication (heparin, low-molecular weight heparin, warfarin, direct oral anticoagulants) during last month pre-surgery
- Emergency operation (e.g. for trauma or infection)
- Age \< 18 years
- Allergy or other contraindication to planned low-molecular weight heparin
- Inability to give written informed consent
- Liver resection not performed (removed from analyses after randomization)
Key Trial Info
Start Date :
February 10 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2027
Estimated Enrollment :
1012 Patients enrolled
Trial Details
Trial ID
NCT04731558
Start Date
February 10 2021
End Date
March 1 2027
Last Update
February 14 2025
Active Locations (7)
Enter a location and click search to find clinical trials sorted by distance.
1
Helsinki University Hospital
Helsinki, Finland
2
Kuopio University Hospital
Kuopio, Finland
3
Oulu University Hospital
Oulu, Finland
4
Tampere University Hospital
Tampere, Finland