Status:
UNKNOWN
Defining the Role of the Skin Microbiome in Immune-related Adverse Events
Lead Sponsor:
University Hospital, Bordeaux
Collaborating Sponsors:
Centre National de la Recherche Scientifique, France
Conditions:
Vitiligo
Skin Melanoma
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The skin microbiome has been implicated in several cutaneous autoimmune pathologies such as psoriasis and atopic dermatitis. However, its role in vitiligo and vitiligo lesions occuring in patients rec...
Detailed Description
Melanoma is the most dangerous skin cancer accounting for the highest skin cancer deaths. The prognosis for metastatic melanoma has improved considerably in recent years thanks to advances in the fiel...
Eligibility Criteria
Inclusion
- Adult patients diagnosed with Vitiligo according to usual criteria.
- Adult patients with metastatic melanoma, under anti-PD-1 who developed vitiligo
- Adult patients with metastatic melanoma who did not develop Immune related adverse events under anti-PD-1
- Adult patients with metastatic melanoma who developed vitiligo under anti-PD-1 and discontinued the treatment
- Free, informed by the participant and the investigator (at the latest on the day of inclusion and before any examination required by the research).
Exclusion
- Patients under 18 years old.
- No treatment for vitiligo in the past 4 weeks
- Patients under legal protection or unable to express their consent.
- Patients not affiliated to a health insurance system.
- Patients deprived of liberty by judiciary or administrative decision or hospitalized without consent or admitted in a sanitary or social institution for another reason than research.
Key Trial Info
Start Date :
May 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2023
Estimated Enrollment :
175 Patients enrolled
Trial Details
Trial ID
NCT04734704
Start Date
May 1 2021
End Date
May 1 2023
Last Update
February 2 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Service de Dermatologie - Hôpital Saint-André
Bordeaux, France, 33075