Status:

UNKNOWN

The Effects of Preoperative Physical Activities on Surgeries

Lead Sponsor:

Chiayi Christian Hospital

Conditions:

Postoperative Pain

Postoperative Nausea and Vomiting

Eligibility:

All Genders

18+ years

Brief Summary

Recommendation is strong on physical activity (PA) in the prehabilitation of Enhanced Recovery After Surgery (ERAS) for various types of surgeries. The evidence is however weak regarding ERAS protocol...

Detailed Description

Despite the increasing knowledge on the mechanisms of incisional inflammation, transmission of nociception signals, peripheral and central sensitization, and on top of the current advancements in phar...

Eligibility Criteria

Inclusion

  • aged ≥18 y/o
  • Enrolled in-patients
  • Patients are scheduled to undergo various operations.
  • The surgeries are expected to last ≥60 minutes
  • Endotracheal intubation or laryngeal mask inhalation general anesthesia.

Exclusion

  • Patients will transferred to the intensive care unit after operations.
  • American Society of Anesthesiology physical status ≥4
  • poorly controlled diabetic mellitus (HA1c ≥9)
  • prolonged corrected QT interval (male ≥0.45 sec, female ≥0.47 sec)
  • Allergy to any opioids (i.e., morphine, fentanyl, pethidine and others) and nonopioids (i.e., selective or nonselective NSAIDs and acetaminophen)
  • Allergy to dexamethasone, granisetron, droperidol, metoclopramide used for prevention of postoperative nausea and vomiting
  • Deaf or unable to speak/understand Taiwanese or Mandarin
  • Failed to recall or uncertain on how many days/times they had spent doing moderate or vigorous physical activity on recent 6 to 8 weeks before receiving surgery.

Key Trial Info

Start Date :

December 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2023

Estimated Enrollment :

5500 Patients enrolled

Trial Details

Trial ID

NCT04739787

Start Date

December 1 2021

End Date

December 1 2023

Last Update

August 24 2021

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