Status:
SUSPENDED
How Muscle and Tendon Properties Contribute to Functional Change Prior to and Following Knee Replacement
Lead Sponsor:
University of British Columbia
Conditions:
Total Knee Arthroplasty
Eligibility:
All Genders
45-85 years
Brief Summary
It is unknown how progressive physiological change in muscle and tendon contributes to loss of functional ability in patients undergoing total knee replacement between referral to surgery, and during ...
Detailed Description
Osteoarthritis leads to degeneration of the articulating surfaces of the femur and tibia, with the end-stage intervention being replacement of these articulating surfaces using a total knee arthroplas...
Eligibility Criteria
Inclusion
- Referred by an orthopedic surgeon to undergo unilateral total knee arthroplasty,
- Age- and sex-matched controls who are not diagnosed with knee or hip osteoarthritis
- Read, speak and understand English
Exclusion
- Prior replacement of a knee or hip joint
- Cardiometabolic or neurological disease beyond typical age-related decline
- Have had quadriceps tendon surgery
- Have had major and recent injury or surgery to either leg in prior 6 months
- Exclusion from electrical stimulation protocol if they have an implanted electronic device
Key Trial Info
Start Date :
February 1 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2024
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT04740073
Start Date
February 1 2021
End Date
December 1 2024
Last Update
February 5 2021
Active Locations (1)
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1
University of British Columbia
Kelowna, British Columbia, Canada, V1V 1V7