Status:
COMPLETED
Anti Inflammatory Treatment of Hypertension
Lead Sponsor:
Affiliated Hospital of North Sichuan Medical College
Collaborating Sponsors:
First Hospitals affiliated to the China PLA General Hospital
Conditions:
Hypertension
Eligibility:
All Genders
18+ years
Phase:
PHASE2
PHASE3
Brief Summary
To investigate the anti-inflammatory effect of amlodipine and levamlodipine in the treatment of hypertension
Detailed Description
A total of 200 inpatients or outpatients in the Department of cardiovascular medicine of the third people's Hospital of Mianyang City from April 2021 to October 2021, who met the diagnostic criteria o...
Eligibility Criteria
Inclusion
- ① In line with the diagnostic criteria of ISH2020 International Guidelines for Practice of Hypertension ② Age \>18 years old, gender is not limited, during the treatment did not take other drugs that will affect blood pressure: such as antidepressants, oral contraceptives, Chinese herbal medicine, etc.; Voluntary participation and signing of informed consent, and can complete all the visit plan.
Exclusion
- (1) Those who do not want to take blood tests; (2) Left ventricular ejection fraction \< 50%, heart rate \<50 beats/min; ③ Acute coronary syndrome (unstable angina pectoris and myocardial infarction); ④ valvular heart disease, congenital heart disease, etc.; Other infectious diseases and malignant tumors; ⑥ Bronchial asthma; ⑦ Abnormal liver function and renal dysfunction (ALT BBB 0 80U/L, CR BBB 1 442mmol/L); Autoimmune diseases or any serious and fatal diseases; ⑨ Receiving lipid-lowering therapy and oral vitamins or antioxidants; They are mentally ill, have no self-awareness, and are unable to express themselves or cooperate with others.
Key Trial Info
Start Date :
May 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 2 2015
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04740840
Start Date
May 1 2010
End Date
May 2 2015
Last Update
February 5 2021
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