Status:
RECRUITING
Evaluation of Association Between Testosterone Levels, Dementia, and Adverse Mental Health Outcomes
Lead Sponsor:
M.D. Anderson Cancer Center
Conditions:
Anxiety Disorder
Depression
Eligibility:
All Genders
Brief Summary
This study evaluates the association between testosterone levels and risk of dementia and adverse mental health outcomes (e.g. depression and anxiety). It is not known whether low testosterone levels ...
Detailed Description
PRIMARY OBJECTIVE: I. To use a Mendelian randomization study design to determine whether genetically predicted decreased testosterone levels are associated with an increased risk of dementia. SECOND...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Have volunteered to participate in institutional or national biobanks, mainly the UK Biobank and the Kaiser Permanente Research Bank, and those that have previously participated in studies that resulted in de-identified clinical and genetic data being make available on public archives, mainly the database of Genotypes and Phenotypes (dbGaP)
- No special populations (adults unable to consent, individuals not yet adults, pregnant women, or prisoners)
Exclusion
Key Trial Info
Start Date :
February 13 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
November 30 2025
Estimated Enrollment :
700000 Patients enrolled
Trial Details
Trial ID
NCT04743466
Start Date
February 13 2020
End Date
November 30 2025
Last Update
August 13 2025
Active Locations (1)
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1
M D Anderson Cancer Center
Houston, Texas, United States, 77030