Status:

RECRUITING

Blood and Urine HPVDNA as Minimally Invasive Biomarkers for Cervical Cancer Detection and Surveillance Following Treatment

Lead Sponsor:

UNC Lineberger Comprehensive Cancer Center

Conditions:

Cervical Cancer

Eligibility:

FEMALE

18+ years

Brief Summary

The purpose of this study is to determine if ctHPVDNA (circulating tumor HPV DNA) can be used as a non-invasive biomarker for identification and treatment monitoring of cervical cancer by characterizi...

Detailed Description

Early stage cervical cancer is managed surgically while chemoradiation is the mainstay for treatment of bulky or advanced stage disease. The primary aim of post-treatment surveillance is to detect ear...

Eligibility Criteria

Inclusion

  • 18 years of age or older on day of signing informed consent
  • New diagnosis of cervical cancer
  • Subject is willing and able to comply with study procedures based on the judgement of the investigator or protocol designee

Exclusion

  • Women who are pregnant

Key Trial Info

Start Date :

May 3 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 15 2027

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT04743674

Start Date

May 3 2024

End Date

January 15 2027

Last Update

May 14 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Melissa Knutsen

Chapel Hill, North Carolina, United States, 27599

2

Kamuzu Central Hospital

Lilongwe, Malawi