Status:

TERMINATED

Post Marketing Trial for Evaluating the Effectiveness of ActiGraft in Treating Lower Extremity Hard To Heal Wounds

Lead Sponsor:

RedDress Ltd.

Conditions:

Wounds

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The study is a prospective, single arm, post- marketing study. The subjects enrolled to the study will receive weekly applications of ActiGraft until complete healing or until investigator's decision ...

Eligibility Criteria

Inclusion

  • Subject is ≥18 years of age
  • Patient with a chronic lower extremity ulcer (i.e DFU, VLU, …)
  • Ulcer duration \>30 days.
  • Ulcer size decreased in less than 30% in the 14 days prior to enrollment, while treated with standard of care (or advanced treatment)
  • Subject must be willing to comply with the protocol including having blood drawn to create the ActiGraft
  • Subject can read and understand the Informed Consent form

Exclusion

  • Presence of active underlying osteomyelitis.
  • Known malignancy in the reference wound bed or margins of the wound
  • Cannot withdraw blood in the required amount technically.
  • Subject is receiving (i.e., within the past 30 days) systemic steroids (more than 10mg per day)
  • Subject has been treated with wound dressings that include growth factors, engineered tissues or skin substitutes (within the past 30 days).
  • Subject has been treated with hyperbaric oxygen, wound VAC or Ozone gas(O3) within the past 5 days or is scheduled to receive during the study

Key Trial Info

Start Date :

March 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2023

Estimated Enrollment :

6 Patients enrolled

Trial Details

Trial ID

NCT04745806

Start Date

March 1 2021

End Date

January 1 2023

Last Update

November 15 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Emek Medical Center

Afula, Israel