Status:

ACTIVE_NOT_RECRUITING

ALICIA (Acalabrutinib in CLL Therapy)

Lead Sponsor:

AstraZeneca

Conditions:

Chronic Lymphocytic Leukemia

Eligibility:

All Genders

18+ years

Brief Summary

This is a multicenter non-interventional observational study conducted with a single hand arm to collect real-world data. In this study, commercially available acalabrutinib will be used as prescribed...

Eligibility Criteria

Inclusion

  • Age ≥18 years
  • Confirmed diagnosis of CLL
  • Patient started treatment with monotherapy acalabrutinib (prescribed by physician decision no more than 4 weeks ago before screening)
  • Capability of providing written Informed Consent Form

Exclusion

  • Patients not corresponded to inclusion criteria
  • Pregnancy
  • Lactation
  • Patients included in open-label trials
  • Previous Bruton tyrosine kinase inhibitors (BTKI) treatment

Key Trial Info

Start Date :

February 3 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

February 28 2026

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT04746950

Start Date

February 3 2021

End Date

February 28 2026

Last Update

December 8 2025

Active Locations (12)

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Page 1 of 3 (12 locations)

1

Research Site

Ufa, Bashkortostan Republic, Russia, 450054

2

Research Site

Kaliningrad, Kaliningrad Oblast, Russia

3

Research Site

Khabarovsk, Khabarovskiy Kray, Russia, 680009

4

Research Site

Syktyvkar, Komi, Russia