Status:
UNKNOWN
Positive Pressure Treadmill Walking for Individuals With Knee Pathology
Lead Sponsor:
Shirley Ryan AbilityLab
Conditions:
Knee Osteoarthritis
Eligibility:
All Genders
50+ years
Phase:
NA
Brief Summary
Our goal is to compare the serum biomarker changes of joint disease that occur in response to partially off-loaded (50%) walking exercise to regular (100%) walking exercise while on a Lower Body Posit...
Detailed Description
The morphology and composition of healthy mature articular cartilage is optimized to its primary function of load transfer and distribution. In the osteoarthritic state however, homeostasis of the kne...
Eligibility Criteria
Inclusion
- Age \> 50 years
- Diagnosis of unilateral or bilateral knee osteoarthritis
- Clinical AND/OR radiographic knee osteoarthritis.
Exclusion
- Age \< 50 years
- History of lower extremity total joint arthroplasty
- Current cardiovascular disease or hypertension that is uncontrolled
- History of neurological disorder that effects lower extremity function (i.e., stroke, peripheral neuropathy, multiple sclerosis, Parkinson's disease)
- Current ankle or hip pain
- Currently pregnant for female participants
- Weight over 400 lbs (181.4 kg), height less than 4'8" (142 cm) or over 6'4" (193 cm), 18.5" (47 cm) hip width, or 58" (147 cm) hip circumference
Key Trial Info
Start Date :
June 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2021
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04747444
Start Date
June 1 2019
End Date
September 1 2021
Last Update
February 10 2021
Active Locations (1)
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1
Shirley Ryan AbilityLab
Chicago, Illinois, United States, 60611