Status:
COMPLETED
Reducing Fall Risk Post Hip Fracture in Mild Cognitive Impairment
Lead Sponsor:
University of British Columbia
Collaborating Sponsors:
Amgen
Conditions:
Hip Fractures
Mild Cognitive Impairment
Eligibility:
All Genders
65+ years
Phase:
NA
Brief Summary
Hip fracture is recognized as one of the most serious consequences of osteoporosis, less than half regain pre-fracture independence. 95% of all hip fractures in older adults are due to falls. Thus, re...
Detailed Description
Hip fracture is recognized as one of the most serious consequences of osteoporosis, less than half regain pre-fracture independence. 95% of all hip fractures in older adults are due to falls. Thus, re...
Eligibility Criteria
Inclusion
- 1) aged 65 or older; 2) sustained a fall-related hip fracture in the last 12 months and have returned home; 3) have preserved general cognition as indicated by a Mini-Mental State Examination (MMSE) score = or \> 20/30; 4) have subjective memory complaints, determined by interview;22 5) score \< 26/30 on the Montreal Cognitive Assessment (MoCA); 6) have an absence of significant functional impairment and no dementia as determined by a physician; 7) are not expected to start, or are stable (i.e., \> 3 months) on a fixed dose of anti-dementia medications (e.g., donepezil, galantamine) during the RCT; 8) are expected to live \> 12 months (based on the geriatricians' expert opinion); 9) can read, write, and speak English with acceptable visual and auditory acuity; 10) are able to walk 3 meters with or without an assistive device; and 1) provide written informed consent.
Exclusion
- 1) diagnosed with or suspected to have (by the geriatrician) a neurodegenerative disease (e.g., Parkinson's disease) or dementia; 2) had a clinical stroke; or 3) have a history indicative of carotid sinus sensitivity (i.e., syncopal falls).
Key Trial Info
Start Date :
May 3 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 9 2024
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT04748354
Start Date
May 3 2021
End Date
May 9 2024
Last Update
November 24 2025
Active Locations (1)
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1
University of British Columbia
Vancouver, British Columbia, Canada