Status:

COMPLETED

Comparison of Efficacy and Tolerability of APD Treatment With Different PD Cyclers

Lead Sponsor:

Fresenius Medical Care Deutschland GmbH

Collaborating Sponsors:

Winicker Norimed GmbH

James Motta, Clinical Research Associate (CRA)

Conditions:

Renal Failure

End Stage Renal Disease

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The study has been designed in order to investigate the performance and safety of the new Silencia PD cycler including the Silencia tubing system in comparison to the PD-Night and Homechoice PD cycler...

Eligibility Criteria

Inclusion

  • Informed consent signed and dated by study patient and investigator/authorised physician
  • CKD patients being treated with APD for at least 3 months
  • Minimum age of 18 years
  • Body weight ≥ 40 kg
  • Fluid status regularly monitored with Body Composition Monitor (BCM)
  • Patients planned to change to the Silencia PD cycler
  • Proper functioning catheter
  • Intraperitoneal Pressure (IPP) ≤ 18 cm H2O for the maximum of TAVO parameter "permitted patient volume"
  • Ability to understand the nature and requirements of the study

Exclusion

  • Patients who have any condition prohibiting the use of BCM, like patients with major amputations (e.g. lower leg)
  • Patients receiving polyglucose containing PD solution
  • Any conditions which could interfere with the patient's ability to comply with the study
  • Patients who suffer from peritonitis/exit site infection during the last 4 weeks
  • Women of childbearing age without effective means of contraception, pregnancy (pregnancy test will be conducted at start and end of study) or lactation period
  • Life expectancy \< 3 months
  • Participation in an interventional clinical study during the preceding 30 days
  • Previous participation in the same study

Key Trial Info

Start Date :

May 31 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 12 2021

Estimated Enrollment :

16 Patients enrolled

Trial Details

Trial ID

NCT04749680

Start Date

May 31 2021

End Date

October 12 2021

Last Update

August 2 2022

Active Locations (4)

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Page 1 of 1 (4 locations)

1

Nephocare La Serena

La Serena, Chile

2

Nephocare Independencia

Santiago, Chile

3

Nephocare Providencia

Santiago, Chile

4

Nephocare San Bernardo

Santiago, Chile