Status:

COMPLETED

A Non-invasive Intervention (BreEStim) for Management of Phantom Limb Pain (PLP) After Limb Amputation (Experiment 2)

Lead Sponsor:

The University of Texas Health Science Center, Houston

Collaborating Sponsors:

National Institute on Disability, Independent Living, and Rehabilitation Research

Conditions:

Pain Management

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

The purpose of this study is to compare the effectiveness of innovative intervention of breathing controlled electrical stimulation (BreEStim) and conventional electrical stimulation (EStim) in manage...

Eligibility Criteria

Inclusion

  • has phantom limb pain (PLP) after amputation of one limb, upper or lower limb;
  • has chronic pain, \>3 months;
  • is stable on oral pain medications at least two weeks. (patients are allowed to continue their pain medications, i.e., no change in pain medications.)

Exclusion

  • currently adjusting oral pain medications for their PLP;
  • has pain, but not PLP (e.g., from inflammation at the incision wound of the residual limb);
  • has a pacemaker, or other metal and/or implanted devices;
  • has cognitive impairment from brain injury or are not able to follow commands, or to give consent;
  • has amputation in multiple limbs;
  • have asthma or other pulmonary diseases;
  • are not medically stable;
  • have preexisting psychiatric disorders;
  • alcohol or drug abuse;
  • have a history of seizures/Epilepsy, or taking benzodiazepines, anticonvulsants, and antidepressants.

Key Trial Info

Start Date :

April 2 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 19 2023

Estimated Enrollment :

17 Patients enrolled

Trial Details

Trial ID

NCT04750538

Start Date

April 2 2021

End Date

May 19 2023

Last Update

March 20 2025

Active Locations (1)

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1

The University of Texas Health Science Center

Houston, Texas, United States, 77030