Status:
COMPLETED
Antibiotic Resistance In Eye Surgeries
Lead Sponsor:
University of California, San Francisco
Conditions:
Antibiotic Resistance
Ocular Surface Microbiome
Eligibility:
All Genders
18-85 years
Phase:
PHASE4
Brief Summary
In this study, the investigators seek to determine the effect of antibiotic use post-surgery on antimicrobial resistance. The investigators will be studying adults (aged 18 or older) who will undergo ...
Detailed Description
Antibiotic use has saved millions of lives globally. However, this comes at the cost of selecting for antibiotic-resistant organisms at the individual and the community level. It is estimated that eve...
Eligibility Criteria
Inclusion
- Over 18 years of age
- Undergoing cataract surgeries that would benefit from intracameral antibiotics
- Able to provide swabs
- Able to provide consent
- Surgery of the second eye occurs at least 8 weeks after surgery of the first eye
Exclusion
- Same-day bilateral cataract surgeries
- On immunosuppression medication such as Prednisone, Methotrexate, Cellcept, or anti-TNF inhibitors within past 3 months
- On systemic antibiotic within past 3 months
- On topical antibiotics within past 8 weeks
- Allergies to fluoroquinolone
- Patients needing glaucoma drainage device or trabeculectomy
- Inability to consent
Key Trial Info
Start Date :
March 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 31 2023
Estimated Enrollment :
108 Patients enrolled
Trial Details
Trial ID
NCT04750655
Start Date
March 1 2021
End Date
August 31 2023
Last Update
March 28 2025
Active Locations (1)
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1
University of California, San Francisco
San Francisco, California, United States, 94158