Status:

UNKNOWN

LUS to Assess Lung Injury After Lung Lobectomy

Lead Sponsor:

Hospital General Universitario de Valencia

Conditions:

Lung Neoplasm

Adult ALL

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of the study is to assess whether lung ultrasound is able to detect lung injury after lung resection surgery.

Detailed Description

Postoperative pulmonary complications (PPC) are common after lung resection surgery, with an incidence that ranges between 11-32%. As PPC are associated with worse outcomes, many studies aim to find p...

Eligibility Criteria

Inclusion

  • Age \> 18
  • ASA I-III
  • Non-small cell lung neoplasm
  • Elective lung lobectomy
  • Under one-lung ventilation

Exclusion

  • Pregnancy
  • Respiratory tract infection the previous month
  • Diagnosed pulmonary fibrosis
  • Predicted FEV \< 40%
  • Surgery that includes resection of the thoracic wall or the diaphragm
  • Neoplasm metastasis
  • Obesity class II or more (BMI ≥ 35 kg/m\^2)
  • Risk of malnutrition CONUT \> 1
  • Hemoglobin \< 10 g/dl
  • Chronic kidney failure: glomerular filtration \< 60 ml/min/m\^2, nephrectomy, kidney transplantation
  • Treatment with corticosteroids or immunosuppressive agents 3 months before surgery
  • Transfusion of blood products during the previous 10 days
  • Heart failure (New York Heart Association Functional Class 3 or 4) during the week before surgery.
  • Heart valve diseases over stage B of the American College of Cardiology/American
  • Heart Association Task Force on Practice Guidelines 2014
  • Diastolic dysfunction

Key Trial Info

Start Date :

January 28 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

October 31 2021

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT04755478

Start Date

January 28 2021

End Date

October 31 2021

Last Update

February 16 2021

Active Locations (1)

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1

Hospital General Universitario de Valencia

Valencia, Spain, 46014