Status:

COMPLETED

Chloride Transfer During Continuous Renal Replacement Therapy in the Intensive Care Unit: a Prospective Observational Cohort Study

Lead Sponsor:

Hospices Civils de Lyon

Conditions:

Acute Kidney Injury

Eligibility:

All Genders

18+ years

Brief Summary

Acute kidney injury (AKI) is a frequently encountered complication in the intensive care unit (ICU), affecting on average 25 to 35% of patients. It is associated with an increased mortality, proportio...

Eligibility Criteria

Inclusion

  • Adult patients (age \> 18 years) affiliated to a social security regimen.
  • Presenting with stage III AKI according to Kidney Disease: Improving Global Outcome (KDIGO) classification28.
  • Treated with continuous RRT (CVVH or CVVD or CVVHDF) for less than 24 hours, whatever the method used.
  • Mechanically ventilated at the time of inclusion in the study.

Exclusion

  • Patients on chronic hemodialysis / peritoneal dialysis.
  • Patients on extracorporeal membrane oxygenation
  • Patients on intermittent hemodialysis (acute or chronic)
  • RRT initiated for a different reason than stage III AKI according to Kidney Disease: Improving Global Outcome (KDIGO) classification
  • Withholding of life sustaining treatment concerning RRT, mechanical ventilation or cardiopulmonary resuscitation.
  • Patients whose life expectancy is lower than 24 hours
  • Patients under guardianship or another juridical protection
  • Patient's or next of kin opposition to participate
  • Patients previously included in the study

Key Trial Info

Start Date :

March 16 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 24 2022

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT04755491

Start Date

March 16 2021

End Date

August 24 2022

Last Update

September 13 2022

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Hôpital de la Croix-Rousse (Hospices Civils de Lyon) / Médecine Intensive - Réanimation

Lyon, France, 69004