Status:

COMPLETED

Safety and Immunogenicity of Oxford AstraZeneca Vaccine Against COVID-19 Infection

Lead Sponsor:

Zagazig University

Conditions:

Vaccine Adverse Reaction

Seroconversion

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

After SARS-COV-2 inactivated vaccine authorization for use in different countries including Egypt, investigating its immunogenicity, safety, and efficacy in preventing COVID-19 infection is highly nee...

Detailed Description

This study will be conducted at Zagazig University hospital. Laboratory work will be implemented at Immunology Research Laboratory at Microbiology and Immunology Department, Faculty of Medicine, Zagaz...

Eligibility Criteria

Inclusion

  • Healthy healthcare workers

Exclusion

  • Healthy healthcare workers' refusal.
  • Pregnancy and lactation.
  • Confirmed acute cases of SARS-CoV-2 Infection
  • Having a history of SARS-CoV-2 infection in the past 3 months.
  • Fever (body temperature \> 37.0 ℃), dry cough, fatigue, nasal obstruction, runny nose, pharyngeal pain, myalgia, diarrhea, shortness of breath and dyspnea occurred within 14 days before vaccination.
  • History of allergy to any vaccines
  • Previous vaccination within the last 30 days

Key Trial Info

Start Date :

February 11 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 22 2021

Estimated Enrollment :

246 Patients enrolled

Trial Details

Trial ID

NCT04756271

Start Date

February 11 2021

End Date

December 22 2021

Last Update

February 9 2022

Active Locations (1)

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Zagazig University Faculty of Medicine

Zagazig, Sharqia Province, Egypt, 44519