Status:

COMPLETED

18F-FDG Uptake Heterogeneity Predicts Pyrotinib Response

Lead Sponsor:

Biyun Wang, MD

Conditions:

HER2-positive Breast Cancer

Eligibility:

FEMALE

18-80 years

Brief Summary

Heterogeneity of 18F-fluorodeoxyglucose (FDG) uptake is a promising marker for predicting response to treatment. This study aimed to evaluate the ability of pretreatment positron emission tomography/c...

Eligibility Criteria

Inclusion

  • Pathologically confirmed HER2 positive breast cancer
  • Treated with Pyrotinib in the metastatic settings
  • Underwent whole-body FDG PET/CT within 4 weeks before the initiation of pyrotinib and capecitabine were included in this study

Exclusion

  • Incomplete medical history
  • Loss of follow up

Key Trial Info

Start Date :

September 1 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 24 2020

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT04756921

Start Date

September 1 2018

End Date

July 24 2020

Last Update

February 16 2021

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Fudan University Shanghai Cancer Center

Shanghai, Shanghai Municipality, China, 200032