Status:
ACTIVE_NOT_RECRUITING
Phase II RCT of an Internet-adaptation of Managing Cancer and Living Meaningfully (iCALM)
Lead Sponsor:
University Health Network, Toronto
Collaborating Sponsors:
University of Ulm
Conditions:
Advanced Cancer
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
iCALM is an online adaptation of a brief, individual, psychosocial intervention called Managing Cancer and Living Meaningfully (CALM) in patients with advanced and metastatic cancer. CALM has been sho...
Detailed Description
Patients with advanced cancer are at risk for depression due to the disease and to side effects from its treatment. Depression in this population decreases quality of life and adherence to treatment a...
Eligibility Criteria
Inclusion
- ≥18 years of age;
- ability to read and write in English;
- able to access the internet.
- not cognitively impaired;
- able to commit to the required online sessions; and
- patients at Princess Margaret Cancer Centre with a confirmed or working diagnosis of advanced or metastatic cancer with an expected survival of 12-18 months \[stage III or IV lung cancer, any stage of pancreatic cancer, unresectable cholangiocarcinoma, unresectable liver cancer, unresectable ampullary or peri-ampullary cancer or other stage IV (metastatic) GI cancer; stage III or IV ovarian and fallopian tube cancers, or other stage IV gynecological (GYNE) cancer; and stage IV breast, genitourinary (GU), sarcoma, melanoma or endocrine cancers\].
Exclusion
- Inability to pass the cognitive screening test (Short Orientation-Memory-Concentration Test (SOMC) score \<20, Katzman et al., 1983); and
- actively receiving a structured or semi-structured psychotherapy at Princess Margaret Cancer Centre
Key Trial Info
Start Date :
October 13 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT04757155
Start Date
October 13 2021
End Date
December 1 2025
Last Update
July 17 2025
Active Locations (1)
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1
Princess Margaret Cancer Centre
Toronto, Ontario, Canada, M5G 2M9