Status:

RECRUITING

Multidimensional Apathy in Psychiatric Pathologies.

Lead Sponsor:

University Hospital, Strasbourg, France

Conditions:

Apathy

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

Apathy is defined by quantitative decrease in goal-directed activity in comparison to the person's previous level of functioning. Apathy is a transnosographic symptom, prevalent in many neurological a...

Eligibility Criteria

Inclusion

  • Inclusion criteria (all subjects):
  • age between 18 and 60 years
  • men or women volunteers, hospitalized or not
  • subject affiliated to an health insurance
  • subject having signed an informed consent
  • Inclusion criteria (for schizophrenic patients):
  • \- presence of DSM-V TR criteria for schizophrenia (American Psychiatric Association, 1994)
  • Inclusion criteria (for depressive patients):
  • \- presence of DSM-V TR criteria for depression (American Psychiatric Association, 1994)

Exclusion

  • a major or non stabilized somatic disorder
  • medical history likely to affect cerebral anatomy or linked to an abnormality (neonatal distress, neurochirurgical intervention, neurological disorders, stroke attack)
  • any disorders involved in the use of a psycho-active substance (as defined by the DSM-IV)
  • sensory disabling impairments, and specifically visual acuity \< 8
  • general anaesthesia during the 3 months before the study
  • pregnancy (declared by the subject)
  • persons in an emergency situation
  • persons deprived in any way of their liberty
  • persons in period of exclusion in an other protocol
  • Exclusion criteria (for controls):
  • \- use of psychotropic substance during the 3 weeks before the study
  • Exclusion criteria (for patients):
  • \- use of benzodiazepines

Key Trial Info

Start Date :

January 5 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 1 2027

Estimated Enrollment :

144 Patients enrolled

Trial Details

Trial ID

NCT04757220

Start Date

January 5 2022

End Date

March 1 2027

Last Update

August 3 2025

Active Locations (1)

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Service de Psychiatrie, Hôpital Civil, Hôpitaux Universitaires de Strasbourg

Strasbourg, France, 67091