Status:
COMPLETED
An Investigation of the Effects of Opioid Receptor Blockade on Changes in Self-esteem and Social Attention
Lead Sponsor:
McGill University
Conditions:
Self Esteem
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to explore the effects of endogenous opioids on self-esteem and attentional bias toward social cues. This is achieved by administering the drug naltrexone, which temporari...
Eligibility Criteria
Inclusion
- good physical health,
- normal kidney and liver function results from within previous year
Exclusion
- allergy to naltrexone
- kidney or liver injury or disorder
- bipolar, panic, or psychotic disorders
- epilepsy
- smoking more than 15 cigarettes per day
- pregnancy
- substance abuse
- use of opioid analgesics, cocaine, recreational drugs (e.g., marijuana, LSD, ecstasy, etc.), or prescription medication (except oral contraceptives) within the past 10 days
- use of over-the-counter drugs (e.g., analgesics, anti-inflammatories, sleeping aids, etc.) or alcohol within the past 24 hours
- current experience of pain (e.g., headache)
- use of anti-diarrheal medications in the 7 days prior to the study.
Key Trial Info
Start Date :
July 9 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 15 2013
Estimated Enrollment :
35 Patients enrolled
Trial Details
Trial ID
NCT04757506
Start Date
July 9 2012
End Date
March 15 2013
Last Update
February 18 2021
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