Status:
UNKNOWN
Transanal Irrigation to Prevent Major Low Anterior Resection Syndrome
Lead Sponsor:
Sixth Affiliated Hospital, Sun Yat-sen University
Conditions:
Low Anterior Resection Syndrome
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
Bowel dysfunction after rectal cancer resection comprises a vast array of bowel symptoms and associated quality-of-life impairment, collectively termed as low anterior resection syndrome (LARS). There...
Eligibility Criteria
Inclusion
- Age: 18-75 years old
- Curative low anterior resection for rectal cancer with diverting stoma
- Stoma closure within 1 month
- Preoperative radiotherapy or height of anastomosis less than 5 cm from anal verge
- No evidence of anastomotic leakage or severe stenosis
Exclusion
- Tumor recurrence or distant metastasis
- Secondary operation with stoma
- Prior disease impairing bowel function except for rectal cancer
- Any contraindication for transanal irrigation
- Pregnant or nursing
- Serious cardiovascular disease, uncontrolled infections, or other serious uncontrolled concomitant disease
- Cognitive or psychological disorder
Key Trial Info
Start Date :
March 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2024
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04758195
Start Date
March 1 2021
End Date
June 30 2024
Last Update
June 29 2023
Active Locations (1)
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1
Sixth Affiliated Hospital, Sun Yat-sen University
Guangzhou, Guangdong, China, 510000